Trabajos de Darío Acuña Castroviejo

Trabajos de Nombre

Clinical Medicine

Listando 19 trabajos del autor/autora 38

Lista de trabajos en el área Clinical Medicine

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Letter A phase II, single-center, double-blind, randomized placebo-controlled trial to explore the efficacy and safety of intravenous melatonin in patients with COVID-19 admitted to the intensive care unit (MelCOVID study): a structured summary of a study protoco Rodriguez-Rubio, Miguel; Figueira, Juan Carlos; Acuna-Castroviejo, Dario; Borobia, Alberto M.; Escames, Germaine; de la Oliva, Pedro TRIALS (2020) DOI / 10.1186/s13063-020-04632-4 Gold DOAJ, Green published

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Editorial Material Clinical trial to test the efficacy of melatonin in COVID-19 Acuna-Castroviejo, Dario; Escames, Germaine; Figueira, Juan C.; de la Oliva, Pedro; Borobia, Alberto M.; Acuna-Fernandez, Carlos JOURNAL OF PINEAL RESEARCH 0742-3098 (2020) DOI / 10.1111/jpi.12683 Green published, Bronze

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Article Melatonin protects rats from radiotherapy-induced small intestine toxicity Fernandez, Beatriz; Moneim, Ahmed E. Abdel; Ortiz, Francisco; Shen, Ying-Qiang; Soto-Mercado, Viviana; Mendivil-Perez, Miguel; Guerra-Librero, Ana; Acuna-Castroviejo, Dario; Molina-Navarro, Maria M.; Garcia-Verdugo, Jose M.; Sayed, Ramy K. A.; Florido, Jav PLOS ONE 1932-6203 (2017) DOI / 10.1371/journal.pone.0174474 Gold DOAJ, Green published

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Article CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome Luna-Sanchez, Marta; Hidalgo-Gutierrez, Agustin; Hildebrandt, Tatjana M.; Chaves-Serrano, Julio; Barriocanal-Casado, Eliana; Santos-Fandila, Angela; Romero, Miguel; Sayed, Ramy K. A.; Duarte, Juan; Prokisch, Holger; Schuelke, Markus; Distelmaier, Felix; Es EMBO MOLECULAR MEDICINE 1757-4676 (2017) DOI / 10.15252/emmm.201606345 Gold DOAJ, Green published

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Article beta-RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9(R239X) mice Hidalgo-Gutierrez, Agustin; Barriocanal-Casado, Eliana; Bakkali, Mohammed; Elena Diaz-Casado, M.; Sanchez-Maldonado, Laura; Romero, Miguel; Sayed, Ramy K.; Prehn, Cornelia; Escames, Germaine; Duarte, Juan; Acuna-Castroviejo, Dario; Lopez, Luis C. EMBO MOLECULAR MEDICINE 1757-4676 (2019) DOI / 10.15252/emmm.201809466 Gold DOAJ, Green published

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Article Rapamycin administration is not a valid therapeutic strategy for every case of mitochondrial disease Barriocanal-Casado, Eliana; Hidalgo-Gutierrez, Agustin; Raimundo, Nuno; Gonzalez-Garcia, Pilar; Acuna-Castroviejo, Dario; Escames, Germaine; Lopez, Luis C. EBIOMEDICINE 2352-3964 (2019) DOI / 10.1016/j.ebiom.2019.03.025 Gold DOAJ, Green published

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Article Effect of Melatonin Supplementation on Antioxidant Status and DNA Damage in High Intensity Trained Athletes Ortiz-Franco, Manuel; Planells, Elena; Quintero, Bartholome; Acuna-Castroviejo, Dario; Rusanova, Iryna; Escames, Germaine; Molina-Lopez, Jorge INTERNATIONAL JOURNAL OF SPORTS MEDICINE 0172-4622 (2017) DOI / 10.1055/s-0043-119881

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Article Melatonin enhances neural stem cell differentiation and engraftment by increasing mitochondrial function Mendivil-Perez, Miguel; Soto-Mercado, Viviana; Guerra-Librero, Ana; Fernandez-Gil, Beatriz I.; Florido, Javier; Shen, Ying-Qiang; Tejada, Miguel A.; Capilla-Gonzalez, Vivian; Rusanova, Iryna; Garcia-Verdugo, Jose M.; Acuna-Castroviejo, Dario; Carlos Lopez, JOURNAL OF PINEAL RESEARCH 0742-3098 (2017) DOI / 10.1111/jpi.12415

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Article The Protective Effect of Melatonin Against Age-Associated, Sarcopenia-Dependent Tubular Aggregate Formation, Lactate Depletion, and Mitochondrial Changes Sayed, Ramy K. A.; Fernandez-Ortiz, Marisol; Diaz-Casado, Maria E.; Rusanova, Iryna; Rahim, Ibtissem; Escames, Germaine; Lopez, Luis C.; Mokhtar, Doaa M.; Acuna-Castroviejo, Dario JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 1079-5006 (2018) DOI / 10.1093/gerona/gly059 Bronze

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Article Lack of NLRP3 Inflammasome Activation Reduces Age-Dependent Sarcopenia and Mitochondrial Dysfunction, Favoring the Prophylactic Effect of Melatonin Sayed, Ramy K. A.; Fernandez-Ortiz, Marisol; Diaz-Casado, Maria E.; Aranda-Martinez, Paula; Fernandez-Martinez, Jose; Guerra-Librero, Ana; Escames, Germaine; Lopez, Luis C.; Alsaadawy, Reem M.; Acuna-Castroviejo, Dario JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 1079-5006 (2019) DOI / 10.1093/gerona/glz079

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Article The benefit of a supplement with the antioxidant melatonin on redox status and muscle damage in resistance-trained athletes Leonardo-Mendonca, Roberto C.; Ocana-Wilhelmi, Javier; De Haro, Tomas; de Teresa-Galvan, Carlos; Guerra-Hernandez, Eduardo; Rusanova, Iryna; Fernandez-Ortiz, Marisol; Sayed, Ramy K. A.; Escames, Germaine; Acuna-Castroviejo, Dario APPLIED PHYSIOLOGY NUTRITION AND METABOLISM 1715-5312 (2017) DOI / 10.1139/apnm-2016-0677

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Review Targeting NLRP3 (Nucleotide-Binding Domain, Leucine-Rich-Containing Family, Pyrin Domain-Containing-3) Inflammasome in Cardiovascular Disorders Wang, Zheng; Hu, Wei; Lu, Chenxi; Ma, Zhiqiang; Jiang, Shuai; Gu, Chunhu; Acuna-Castroviejo, Dario; Yang, Yang ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 1079-5642 (2018) DOI / 10.1161/atvbaha.118.311916 Bronze

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Article beta-RA Targets Mitochondrial Metabolism and Adipogenesis, Leading to Therapeutic Benefits against CoQ Deficiency and Age-Related Overweight Hidalgo-Gutierrez, Agustin; Barriocanal-Casado, Eliana; Diaz-Casado, Maria Elena; Gonzalez-Garcia, Pilar; Zenezini Chiozzi, Riccardo; Acuna-Castroviejo, Dario; Lopez, Luis Carlos BIOMEDICINES (2021) DOI / 10.3390/biomedicines9101457 Gold, Green submitted, Green published

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Article Melatonin administration to wild-type mice and nontreated NLRP3 mutant mice share similar inhibition of the inflammatory response during sepsis Rahim, Ibtissem; Djerdjouri, Bahia; Sayed, Ramy K.; Fernandez-Ortiz, Marisol; Fernandez-Gil, Beatriz; Hidalgo-Gutierrez, Agustin; Lopez, Luis C.; Escames, Germaine; Reiter, Russel J.; Acuna-Castroviejo, Dario JOURNAL OF PINEAL RESEARCH 0742-3098 (2017) DOI / 10.1111/jpi.12410

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Review Involvement of plasma miRNAs, muscle miRNAs and mitochondrial miRNAs in the pathophysiology of frailty Rusanova, Iryna; Fernandez-Martinez, Jose; Fernandez-Ortiz, Marisol; Aranda-Martinez, Paula; Escamesa, Germaine; Garcia-Garcia, Francisco J.; Manas, Leocadio; Acuna-Castroviejo, Dario EXPERIMENTAL GERONTOLOGY 0531-5565 (2019) DOI / 10.1016/j.exger.2019.110637

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Article Daily Changes in the Expression of Clock Genes in Sepsis and Their Relation with Sepsis Outcome and Urinary Excretion of 6-Sulfatoximelatonin Acuna-Fernandez, Carlos; Solera Marin, Jorge; Diaz-Casado, Maria E.; Rusanova, Iryna; Darias-Delbey, Beneharo; Perez-Guillama, Luis; Florido-Ruiz, Javier; Acuna-Castroviejo, Dario SHOCK 1073-2322 (2020) DOI / 10.1097/shk.0000000000001433

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Article Retinoid-related orphan nuclear receptor alpha (ROR alpha)-deficient mice display morphological testicular defects Sayed, Ramy K. A.; Mokhtar, Doaa M.; Fernandez-Ortiz, Marisol; Escames, Germaine; Acuna-Castroviejo, Dario LABORATORY INVESTIGATION 0023-6837 (2019) DOI / 10.1038/s41374-019-0299-5

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Article Lack of retinoid acid receptor-related orphan receptor alpha accelerates and melatonin supplementation prevents testicular aging Sayed, Ramy K. A.; Mokhtar, Doaa M.; Fernandez-Ortiz, Marisol; Fernandez-Martinez, Jose; Aranda-Martinez, Paula; Escames, Germaine; Acuna-Castroviejo, Dario AGING-US 1945-4589 (2020) DOI / 10.18632/aging.103654 Green published

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Article Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation Shen, Ying-Qiang; Guerra-Librero, Ana; Fernandez-Gil, Beatriz I.; Florido, Javier; Garcia-Lopez, Sergio; Martinez-Ruiz, Laura; Mendivil-Perez, Miguel; Soto-Mercado, Viviana; Acuna-Castroviejo, Dario; Ortega-Arellano, Hector; Carriel, Victor; Diaz-Casado, M JOURNAL OF PINEAL RESEARCH 0742-3098 (2018) DOI / 10.1111/jpi.12461