Trabajos de Germaine Escames Rosa

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  Listando 29 trabajos del autor/autora 38
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Letter A phase II, single-center, double-blind, randomized placebo-controlled trial to explore the efficacy and safety of intravenous melatonin in patients with COVID-19 admitted to the intensive care unit (MelCOVID study): a structured summary of a study protoco Rodriguez-Rubio, Miguel; Figueira, Juan Carlos; Acuna-Castroviejo, Dario; Borobia, Alberto M.; Escames, Germaine; de la Oliva, Pedro TRIALS (2020) DOI / 10.1186/s13063-020-04632-4 Gold DOAJ, Green published
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Editorial Material Clinical trial to test the efficacy of melatonin in COVID-19 Acuna-Castroviejo, Dario; Escames, Germaine; Figueira, Juan C.; de la Oliva, Pedro; Borobia, Alberto M.; Acuna-Fernandez, Carlos JOURNAL OF PINEAL RESEARCH 0742-3098 (2020) DOI / 10.1111/jpi.12683 Green published, Bronze
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Article Melatonin protects rats from radiotherapy-induced small intestine toxicity Fernandez, Beatriz; Moneim, Ahmed E. Abdel; Ortiz, Francisco; Shen, Ying-Qiang; Soto-Mercado, Viviana; Mendivil-Perez, Miguel; Guerra-Librero, Ana; Acuna-Castroviejo, Dario; Molina-Navarro, Maria M.; Garcia-Verdugo, Jose M.; Sayed, Ramy K. A.; Florido, Jav PLOS ONE 1932-6203 (2017) DOI / 10.1371/journal.pone.0174474 Gold DOAJ, Green published
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Review Protective Effects of Melatonin on the Skin: Future Perspectives Rusanova, Iryna; Martinez-Ruiz, Laura; Florido, Javier; Rodriguez-Santana, Cesar; Guerra-Librero, Ana; Acuna-Castroviejo, Dario; Escames, Germaine INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 (2019) DOI / 10.3390/ijms20194948 Gold, Green published
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Article CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome Luna-Sanchez, Marta; Hidalgo-Gutierrez, Agustin; Hildebrandt, Tatjana M.; Chaves-Serrano, Julio; Barriocanal-Casado, Eliana; Santos-Fandila, Angela; Romero, Miguel; Sayed, Ramy K. A.; Duarte, Juan; Prokisch, Holger; Schuelke, Markus; Distelmaier, Felix; Es EMBO MOLECULAR MEDICINE 1757-4676 (2017) DOI / 10.15252/emmm.201606345 Gold DOAJ, Green published
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Article Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases Lopez, Ana; Ortiz, Francisco; Doerrier, Carolina; Venegas, Carmen; Fernandez-Ortiz, Marisol; Aranda-Martinez, Paula; Diaz-Casado, Maria E.; Fernandez-Gil, Beatriz; Barriocanal-Casado, Eliana; Escames, Germaine; Lopez, Luis C.; Acuna-Castroviejo, Dario PLOS ONE 1932-6203 (2017) DOI / 10.1371/journal.pone.0183090 Gold DOAJ, Green published
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Review Oral Mucositis: Melatonin Gel an Effective New Treatment Moneim, Ahmed Esmat Abdel; Guerra-Librero, Ana; Florido, Javier; Shen, Ying-Qiang; Fernandez-Gil, Beatriz; Acuna-Castroviejo, Dario; Escames, Germaine INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 (2017) DOI / 10.3390/ijms18051003 Gold DOAJ, Green published
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Article Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism Gonzalez-Garcia, Pilar; Hidalgo-Gutierrez, Agustin; Mascaraque, Cristina; Barriocanal-Casado, Eliana; Bakkali, Mohammed; Ziosi, Marcello; Botagoz Abdihankyzy, Ussipbek; Sanchez-Hernandez, Sabina; Escames, Germaine; Prokisch, Holger; Martin, Francisco; Quin HUMAN MOLECULAR GENETICS 0964-6906 (2020) DOI / 10.1093/hmg/ddaa214 Green published, Hybrid
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Article beta-RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9(R239X) mice Hidalgo-Gutierrez, Agustin; Barriocanal-Casado, Eliana; Bakkali, Mohammed; Elena Diaz-Casado, M.; Sanchez-Maldonado, Laura; Romero, Miguel; Sayed, Ramy K.; Prehn, Cornelia; Escames, Germaine; Duarte, Juan; Acuna-Castroviejo, Dario; Lopez, Luis C. EMBO MOLECULAR MEDICINE 1757-4676 (2019) DOI / 10.15252/emmm.201809466 Gold DOAJ, Green published
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Review Coronavirus Disease 2019 (COVID-19) and Its Neuroinvasive Capacity: Is It Time for Melatonin? Romero, Alejandro; Ramos, Eva; Lopez-Munoz, Francisco; Gil-Martin, Emilio; Escames, Germaine; Reiter, Russel J. CELLULAR AND MOLECULAR NEUROBIOLOGY 0272-4340 (2020) DOI / 10.1007/s10571-020-00938-8 Bronze, Green submitted, Green published
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Article Rapamycin administration is not a valid therapeutic strategy for every case of mitochondrial disease Barriocanal-Casado, Eliana; Hidalgo-Gutierrez, Agustin; Raimundo, Nuno; Gonzalez-Garcia, Pilar; Acuna-Castroviejo, Dario; Escames, Germaine; Lopez, Luis C. EBIOMEDICINE 2352-3964 (2019) DOI / 10.1016/j.ebiom.2019.03.025 Gold DOAJ, Green published
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Article Effect of Melatonin Supplementation on Antioxidant Status and DNA Damage in High Intensity Trained Athletes Ortiz-Franco, Manuel; Planells, Elena; Quintero, Bartholome; Acuna-Castroviejo, Dario; Rusanova, Iryna; Escames, Germaine; Molina-Lopez, Jorge INTERNATIONAL JOURNAL OF SPORTS MEDICINE 0172-4622 (2017) DOI / 10.1055/s-0043-119881
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Article Melatonin enhances neural stem cell differentiation and engraftment by increasing mitochondrial function Mendivil-Perez, Miguel; Soto-Mercado, Viviana; Guerra-Librero, Ana; Fernandez-Gil, Beatriz I.; Florido, Javier; Shen, Ying-Qiang; Tejada, Miguel A.; Capilla-Gonzalez, Vivian; Rusanova, Iryna; Garcia-Verdugo, Jose M.; Acuna-Castroviejo, Dario; Carlos Lopez, JOURNAL OF PINEAL RESEARCH 0742-3098 (2017) DOI / 10.1111/jpi.12415
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Article Analysis of Plasma MicroRNAs as Predictors and Biomarkers of Aging and Frailty in Humans Rusanova, Iryna; Diaz-Casado, Maria E.; Fernandez-Ortiz, Marisol; Aranda-Martinez, Paula; Guerra-Librero, Ana; Garcia-Garcia, Francisco J.; Escames, Germaine; Manas, Leocadio; Acuna-Castroviejo, Dario OXIDATIVE MEDICINE AND CELLULAR LONGEVITY 1942-0900 (2018) DOI / 10.1155/2018/7671850 Green published, Gold other
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Article The Protective Effect of Melatonin Against Age-Associated, Sarcopenia-Dependent Tubular Aggregate Formation, Lactate Depletion, and Mitochondrial Changes Sayed, Ramy K. A.; Fernandez-Ortiz, Marisol; Diaz-Casado, Maria E.; Rusanova, Iryna; Rahim, Ibtissem; Escames, Germaine; Lopez, Luis C.; Mokhtar, Doaa M.; Acuna-Castroviejo, Dario JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 1079-5006 (2018) DOI / 10.1093/gerona/gly059 Bronze
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Article The Impact of Melatonin Supplementation and NLRP3 Inflammasome Deletion on Age-Accompanied Cardiac Damage Sayed, Ramy K. A.; Fernandez-Ortiz, Marisol; Rahim, Ibtissem; Fernandez-Martinez, Jose; Aranda-Martinez, Paula; Rusanova, Iryna; Martinez-Ruiz, Laura; Alsaadawy, Reem M.; Escames, Germaine; Acuna-Castroviejo, Dario ANTIOXIDANTS (2021) DOI / 10.3390/antiox10081269 Gold, Green published
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Article Lack of NLRP3 Inflammasome Activation Reduces Age-Dependent Sarcopenia and Mitochondrial Dysfunction, Favoring the Prophylactic Effect of Melatonin Sayed, Ramy K. A.; Fernandez-Ortiz, Marisol; Diaz-Casado, Maria E.; Aranda-Martinez, Paula; Fernandez-Martinez, Jose; Guerra-Librero, Ana; Escames, Germaine; Lopez, Luis C.; Alsaadawy, Reem M.; Acuna-Castroviejo, Dario JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 1079-5006 (2019) DOI / 10.1093/gerona/glz079
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Article The benefit of a supplement with the antioxidant melatonin on redox status and muscle damage in resistance-trained athletes Leonardo-Mendonca, Roberto C.; Ocana-Wilhelmi, Javier; De Haro, Tomas; de Teresa-Galvan, Carlos; Guerra-Hernandez, Eduardo; Rusanova, Iryna; Fernandez-Ortiz, Marisol; Sayed, Ramy K. A.; Escames, Germaine; Acuna-Castroviejo, Dario APPLIED PHYSIOLOGY NUTRITION AND METABOLISM 1715-5312 (2017) DOI / 10.1139/apnm-2016-0677
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Article Melatonin Targets Metabolism in Head and Neck Cancer Cells by Regulating Mitochondrial Structure and Function Guerra-Librero, Ana; Fernandez-Gil, Beatriz I.; Florido, Javier; Martinez-Ruiz, Laura; Rodriguez-Santana, Cesar; Shen, Ying-Qiang; Garcia-Verdugo, Jose M.; Lopez-Rodriguez, Alba; Rusanova, Iryna; Quinones-Hinojosa, Alfredo; Acuna-Castroviejo, Dario; Marrue ANTIOXIDANTS (2021) DOI / 10.3390/antiox10040603 Gold DOAJ, Green published
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Article Melatonin administration to wild-type mice and nontreated NLRP3 mutant mice share similar inhibition of the inflammatory response during sepsis Rahim, Ibtissem; Djerdjouri, Bahia; Sayed, Ramy K.; Fernandez-Ortiz, Marisol; Fernandez-Gil, Beatriz; Hidalgo-Gutierrez, Agustin; Lopez, Luis C.; Escames, Germaine; Reiter, Russel J.; Acuna-Castroviejo, Dario JOURNAL OF PINEAL RESEARCH 0742-3098 (2017) DOI / 10.1111/jpi.12410
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Review Melatonin, clock genes and mitochondria in sepsis Acuna-Castroviejo, Dario; Rahim, Ibtissem; Acuna-Fernandez, Carlos; Fernandez-Ortiz, Marisol; Solera-Marin, Jorge; Sayed, Ramy K. A.; Diaz-Casado, Maria E.; Rusanova, Iryna; Lopez, Luis C.; Escames, Germaine CELLULAR AND MOLECULAR LIFE SCIENCES 1420-682X (2017) DOI / 10.1007/s00018-017-2610-1
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Article The Impact of Melatonin and NLRP3 Inflammasome on the Expression of microRNAs in Aged Muscle Sayed, Ramy K. A.; Fernandez-Ortiz, Marisol; Fernandez-Martinez, Jose; Aranda Martinez, Paula; Guerra-Librero, Ana; Rodriguez-Santana, Cesar; De Haro, Tomas; Escames, Germaine; Acuna-Castroviejo, Dario; Rusanova, Iryna ANTIOXIDANTS (2021) DOI / 10.3390/antiox10040524 Gold DOAJ, Green published
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Article Melatonin/Nrf2/NLRP3 Connection in Mouse Heart Mitochondria during Aging Fernandez-Ortiz, Marisol; Sayed, Ramy K. A.; Fernandez-Martinez, Jose; Cionfrini, Antonia; Aranda-Martinez, Paula; Escames, Germaine; De Haro, Tomas; Acuna-Castroviejo, Dario ANTIOXIDANTS (2020) DOI / 10.3390/antiox9121187 Gold, Green published
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Article Lack of retinoid acid receptor-related orphan receptor alpha accelerates and melatonin supplementation prevents testicular aging Sayed, Ramy K. A.; Mokhtar, Doaa M.; Fernandez-Ortiz, Marisol; Fernandez-Martinez, Jose; Aranda-Martinez, Paula; Escames, Germaine; Acuna-Castroviejo, Dario AGING-US 1945-4589 (2020) DOI / 10.18632/aging.103654 Green published
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Article Melatonin Enhances Cisplatin and Radiation Cytotoxicity in Head and Neck Squamous Cell Carcinoma by Stimulating Mitochondrial ROS Generation, Apoptosis, and Autophagy Fernandez-Gil, Beatriz, I; Guerra-Librero, Ana; Shen, Ying-Qiang; Florido, Javier; Martinez-Ruiz, Laura; Garcia-Lopez, Sergio; Adan, Christian; Rodriguez-Santana, Cesar; Acuna-Castroviejo, Dario; Quinones-Hinojosa, Alfredo; Fernandez-Martinez, Jose; Moneim OXIDATIVE MEDICINE AND CELLULAR LONGEVITY 1942-0900 (2019) DOI / 10.1155/2019/7187128 Gold DOAJ, Green published
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Article Retinoid-related orphan nuclear receptor alpha (ROR alpha)-deficient mice display morphological testicular defects Sayed, Ramy K. A.; Mokhtar, Doaa M.; Fernandez-Ortiz, Marisol; Escames, Germaine; Acuna-Castroviejo, Dario LABORATORY INVESTIGATION 0023-6837 (2019) DOI / 10.1038/s41374-019-0299-5
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Article Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation Shen, Ying-Qiang; Guerra-Librero, Ana; Fernandez-Gil, Beatriz I.; Florido, Javier; Garcia-Lopez, Sergio; Martinez-Ruiz, Laura; Mendivil-Perez, Miguel; Soto-Mercado, Viviana; Acuna-Castroviejo, Dario; Ortega-Arellano, Hector; Carriel, Victor; Diaz-Casado, M JOURNAL OF PINEAL RESEARCH 0742-3098 (2018) DOI / 10.1111/jpi.12461
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Article Melatonin alleviates sepsis-induced heart injury through activating the Nrf2 pathway and inhibiting the NLRP3 inflammasome Rahim, Ibtissem; Sayed, Ramy K.; Fernandez-Ortiz, Marisol; Aranda-Martinez, Paula; Guerra-Librero, Ana; Fernandez-Martinez, Jose; Rusanova, Iryna; Escames, Germaine; Djerdjouri, Bahia; Acuna-Castroviejo, Dario NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 0028-1298 (2020) DOI / 10.1007/s00210-020-01972-5
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Article Randomized placebo-controlled phase II trial of high-dose melatonin mucoadhesive oral gel for the prevention and treatment of oral mucositis in patients with head and neck cancer undergoing radiation therapy concurrent with systemic treatment Lozano, A.; Marruecos, J.; Rubio, J.; Farre, N.; Gomez-Millan, J.; Morera, R.; Planas, I.; Lanzuela, M.; Vazquez-Masedo, M. G.; Cascallar, L.; Giralt, J.; Escames, G.; Valenti, V.; Grima, P.; Bosser, R.; Tarrago, C.; Mesia, R. CLINICAL & TRANSLATIONAL ONCOLOGY 1699-048X (2021) DOI / 10.1007/s12094-021-02586-w